Python Mass Mail Software Fast and Reliable

I want to have a Powerful reliable and fast Python mail script to be created for mass mailing OPT-IN emails and Newsletters. Creating a unique MTA more indebt then QMail or a (Twisted-based MTA). Regular Mailer Options need to be implemented along with a few more options. Option to retrieve sourced email list and proxy list from url/csv/txt file and multiple sessions. I would like to be able the speed of the mailer RPM Rate Per Mintue/Hour. Along with veiwing the mailers speed. Option to modify the entire header or leave as is using with or without DomainKeys/SPF. Web-based Gui of some sort will need to be made to control and change settings with mail script. Implememitation of Unsubscripe-Suppression options etc. Please have experience creating one of these scripts. We can chat more in dept about what exactly I want and what needs to be implemented. I am posting some videos of a mailer I would like to duplicate but make it my own with other options. [login to view URL] [login to view URL] Keywords for programmer: (read: async event loop based, Twisted-MTA, DomainKey, Async)