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@jleslie17
Membro desde 15 de março de 2016
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jleslie17

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I am a freelance data scientist with a strong background (and PhD) in biomedical research. My work relies heavily on data analysis, including examining large and often-messy data sets and utilizing techniques such as machine learning, building regression models, exploratory data analysis and the development of interactive apps and data visualizations. The majority of my analyses are performed in the statistical programming language R. I also have experience using Python and Octave/MatLab. Please see my portfolio for some of my more recent data science projects. I am looking for any projects that will give me more professional experience. At the moment, I am mostly interested in learning new fields within data science and data analytics and building up my portfolio. I am a native English speaker and have extensive experience in preparing scientific presentations and reports. I am available on short notice and keen to hear from you if you have a project that I could contribute to.
$45 USD/hr
4 comentários
3.6
  • 100%Trabalhos Concluídos
  • 100%No orçamento
  • 100%No Prazo
  • 33%Taxa de Recontratação

Portfólio

Comentários recentes

  • image of milesbennington Project for jleslie17 £190.00 GBP

    “Jon was great. Great knowledge and what he doesn't know immediately he can research.”

  • image of fredcostabrava Project for jleslie17 -- 3 $50.00 USD

    “Excellent job!”

  • image of fredcostabrava Project for jleslie17 $150.00 USD

    “HIGHLY RECOMMENDED! It was a pleasure to work with you Jon! Thanks again!”

  • image of fredcostabrava Project for jleslie17 -- 2 $150.00 USD

    “Excellent - a true professional - reliable, flexible and very talented”

Experiência

Postdoctoral Research Associate

May 2012 - Jun 2015 (3 years)

I performed biomedical research on signalling pathways controlling tissue induction in early embryos.

Postdoctoral Research Associate

Nov 2008 - Mar 2012 (3 years)

I performed biomedical research into the gene regulatory networks controlling skeletal muscle formation. This work was based on a DNA microarray project, giving me hands-on experience in R programming and datasets on the order of 1 million observations.

PhD Student and Postdoctoral Fellow

Jul 2003 - Oct 2008 (5 years)

I performed biomedical research into the processes controlling blood vessel formation during embryonic development and in cancer.

Technical Assistant

Aug 2000 - Jun 2003 (2 years)

I performed biomedical research into the molecular mechanisms controlling cell migration.

Educação

PhD

2003 - 2007 (4 years)

BS

1990 - 1994 (4 years)

Publicações

From Mef2 to Vinculin: cell adhesion proteins mediate Mef2-driven sarcomere assembly

Leslie JD, Hughes S. From Mef2 to Vinculin: cell adhesion proteins mediate Mef2-driven sarcomere assembly. In preparation.

Complement in animal development: Unexpected roles of a highly conserved pathway

Leslie JD, Mayor R (2013). Complement in animal development: Unexpected roles of a highly conserved pathway. Seminars in Immunology 25: 39-46.

Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish

Pascoal S, Esteves de Lima J, Leslie JD, Hughes SM, Saúde L (2013). Notch signalling is required for the formation of structurally stable muscle fibres in zebrafish. PLoS One 8 (6): 1-10.

Fish muscle growth and repair: models linking biomedicine and aquaculture

Knight K, Leslie J, de la Serrana DG, von Hofsten J (2011). The company of biologists' workshop - fish muscle growth and repair: models linking biomedicine and aquaculture. J Exp Biol. 214(Pt 18): 2995-6.

Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis

Phng L, Potente M, Leslie JD, Babbage J, Nyqvist D, Lobov I, Ondr JK, Rao S, Lang RA, Thurston G, Gerhardt H (2009). Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis. Dev. Cell 16: 70-82.

Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions...

Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox, KS, Leppert MF (2008). Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol 586 (14): 3405-3423.

Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis

Leslie JD, Ariza-McNaughton L, Bermange AL, McAdow R, Johnson SL, Lewis J (2007). Endothelial signalling by the Notch ligand Delta-like 4 restricts angiogenesis. Development 134: 839-844.

Ena/VASP is Required for Neuritogenesis in the Developing Cortex

Kwiatkowski AV, Rubinson DA, Dent E, van Veen JE, Leslie JD, Zhang J, Mebrane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fässler R, Gertler FB (2007). Ena/VASP is Required for Neuritogenesis in the Developing Cortex. Neuron 56: 441-455.

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding...

Wright GJ*, Leslie JD*, Ariza-McNaughton L, Lewis J (2004). Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development. Development 131 (22): 5659-5669.

Lamellipodin, an Eva/VASP ligand, is implicated in the regulation of lamellipodial dynamics

Krause M, Leslie JD, Stewart M, Lafuente EM, Valderrama F, Jagannathan R, Strasser GA, Rubinson DA, Liu H, Way M, Yaffe MB, Boussiotis VA, Gertler FB (2004). Lamellipodin, an Eva/VASP ligand, is implicated in the regulation of lamellipodial dynamics. Dev. Cell 7 (4): 571-583.

KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions...

Singh NA, Westenskow P, Charlier C, Pappas C, Leslie J, Dillon J, Anderson VE, Sanguinetti MC, Leppert MF (2003). KCNQ2 and KCNQ3 potassium channel genes in benign familial neonatal convulsions: expansion of the functional and mutation spectrum. Brain 126 (12): 2726-2737.

The beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein

Perou CM, Leslie JD, Green W, Li L, Ward DM, Kaplan J (1997). The beige/Chediak-Higashi syndrome gene encodes a widely expressed cytosolic protein. J. Biol. Chem. 272, (47): 29790-29794.

Homotypic lysosome fusion in macrophages: analysis using an in vitro assay

Ward, DM, Leslie, JD, and Kaplan, J (1997). Homotypic lysosome fusion in macrophages: analysis using an in vitro assay. J. Cell Biol. 139, (3): 665-673.

In situ immunocytochemical evidence that a homolog of elongation factor EF-1-alpha is associated...

Durso NA, Leslie JD, and Cyr RJ (1996). In situ immunocytochemical evidence that a homolog of elongation factor EF-1-alpha is associated with microtubules in carrot cells. Protoplasma 190, 141-150.

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