software mailer

hello i need a mailing software which will have 2 mailing options 1) smtp and 2) proxy ip with port # - i have another software which gets me socks 5 proxies for mail - also mailer will have the ability to connect to mysql on my linux server to verify if clients account is active or not - for active we can indicate 1 in mysql - for non active we can indicate 0 in mysql database - i will have a linux server with mysql access - we could use clients email address for activation purpose of the software