Nav K.

The emergence of multi-drug-resistant bacterial pathogens along with labor-intensive and time-consuming drug discovery methods has put an emphasis on alternative approaches which can overcome these drawbacks. One such approach is in silico identification of novel bacterial inhibitors using structure-based drug design methodology. In the present study, novel inhibitors have been proposed against two essential enzymes (MurA and MurZ) involved in the biosynthesis of cell wall of Enterococcus faecalis, a seriou